Mississippi has one warehouse — run by a contractor — that sells all the liquor for the entire state of 2.9 million people. "If a restaurant or store anywhere in Mississippi wanted a bottle of Jim Beam, they had to order it from the wholesale warehouse," reports the Washington Post. But then Mississippi's warehouse-managing contractor implemented a new computer system that wasn't compatible with the state's delivery system (like they'd promised it would be back in 2023). And then things got even worse... "The problem, business owners allege, is that the company tore out the conveyor belts but didn't hire humans to replace them." In February a state Revenue Department commissioner told lawmakers the state was hiring temporary replacement workers, but in the five weeks through March 29th they'd only managed to reduce "pending" orders by 21.7%, from 218,851 down to 171,190, according to stats from Mississippi Today. At least four Mississippi businesses are now suing the warehouse operator "claiming breach of contract and harm to their business." So what's it like in a state suddenly running dry? The Washington Post reports: Willie the one-eyed skeleton is dressed for Cinco de Mayo, but the liquor store where Willie sits ran out of Jose Cuervo months ago. Arrow Wine and Spirits is also out of Tito's and Burnett's vodka, Franzia boxed wine, Jack Daniels, and every kind of premixed margarita... Restaurants in Jackson had no wine on Valentine's Day, and bars on the Gulf Coast ran dry before Mardi Gras. At least five liquor shops have closed, and if cheap pints don't hit the corner stores soon, many of them will, too... [A]s both the state and its businesses lose millions in revenue, many say they see no real end to the crisis. Nearly 174,000 cases of alcohol are sitting in a warehouse north of Jackson, but no one seems to know how to get them out the door... Even the shops that have received deliveries say they often get the wrong thing — Jell-O shots, for instance, that should have been small-batch Norwegian gin... At Willie the one-eyed skeleton's liquor store they'd previously made 300 to 400 sales a day, according to the article, but last week had 34 customers. And Mississippi is one of 17 U.S. states requiring liquor stores to buy their liquor from distribution centers controlled by the state's Department of Revenue... Mississippi Today points out that while some want the state to finally privatize liquor distribution, "The state collects around $120 million a year in taxes on alcohol." Plus the state has already authorized "borrowing $95 million to construct a new warehouse, set to begin operations in 2027..." Thanks to Slashdot reader jrnvk for sharing the news.

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Britain has lost more than 14,000 pubs since 2009, a decline from roughly 54,000 registered public houses and bars to under 40,000 by 2022, according to a new analysis of UK business register data by data analyst Lauren Leek. The North East, North West, Yorkshire and the Midlands lost 25 to 30% of their stock; London saw the smallest decline. Leek trained a random forest model on 49,840 pubs and found spatial isolation -- how far a pub stood from its nearest neighbour -- was the single strongest predictor of closure. Median nearest-neighbour distance for surviving pubs is roughly 280 metres; for closed pubs, 640 metres. Each closure pushes remaining pubs further into isolation, a dynamic Leek calls a "spatial death spiral." Much of that isolation traces to ownership. Stonegate, Britain's largest pub company and a holding of PE firm TDR Capital, carries over $4 billion in debt from its 2019 leveraged acquisition of Ei Group. PE-backed and overseas-owned companies now control roughly a quarter to a third of all British pubs.

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An anonymous reader shares a report: Ever since the federal government began issuing the Dietary Guidelines in 1980, it has told Americans to limit themselves to one or two standard alcoholic drinks a day. Over time, the official advice morphed to no more than two drinks a day for men, and no more than one for women. No longer [non-paywalled source]. The updated guidelines issued on Wednesday say instead that people should consume less alcohol "for better overall health" and "limit alcohol beverages," but they do not recommend clear limits. The guidelines also no longer warn that alcohol may heighten the risk of breast cancer and other malignancies. It is the first time in decades that the government has omitted the daily caps on drinking that define moderate consumption -- standards that are used as benchmarks in clinical studies, to steer medical advice, and to distinguish moderate from heavy drinking, which is unquestionably harmful. The new guidance advises Americans who are pregnant, struggle with alcohol use disorder or take medications that interact with alcohol to avoid drinking altogether. The guidelines also warn people with alcoholism in the family to "be mindful of alcohol consumption and associated addictive behaviors." They do not, however, distinguish between men and women, who metabolize alcohol differently, nor do they caution against underage drinking. The guidelines also no longer include a warning that was in the last set issued in 2020: that even moderate drinking may increase the risk of cancer and some forms of cardiovascular disease, as well as the overall risk of dying.

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An anonymous reader quotes a report from the New York Times: For a while, it seemed the notion that light drinking was good for the heart had gone by the wayside, debunked by new studies and overshadowed by warnings that alcohol causes cancer. Now the American Heart Association has revived the idea in a scientific review that is drawing intense criticism, setting off a new round of debate about alcohol consumption. The paper, which sought to summarize the latest research and was aimed at practicing cardiologists, concluded that light drinking -- one to two drinks a day -- posed no risk for coronary disease, stroke, sudden death and possibly heart failure, and may even reduce the risk of developing these conditions. Controversy over the influential organization's review has been simmering since it was published in the association's journal Circulation in July. Public health groups and many doctors have warned on the basis of recent studies that alcohol can be harmful even in small amounts. Groups like the European Heart Network and the World Heart Federation have stressed that even modest drinking increases the odds of cardiovascular disease. "It says in all our guidelines right now, 'If you don't drink, don't start.' There's not enough evidence to suggest conclusively that it prevents heart disease," said Dr. Mariell Jessup, the chief science and medical officer at the heart association, adding that the review was not meant to serve as a guideline and that the group's advice to patients has not changed. Critics argue that suggesting any heart-health benefits from alcohol is dangerous given its well-documented risks, and they accuse the heart association of selectively weighing studies. They also say a past tie to the alcohol industry by one author should have disqualified him from participating. "The cardiovascular benefits of moderate drinking are questionable at best," said Dr. Elizabeth Farkouh, an internist and alcohol researcher. "But even if there was a benefit, there are so many other ways to reduce cardiovascular risk that don't come with an associated cancer risk." The new review's conclusion is also at odds with the CDC's guidance on alcohol, which notes that "even moderate drinking may increase your risk of death and other alcohol-related harms, compared to not drinking." It also seems to diverge from the heart association's diet and lifestyle recommendation to consume "limited or preferably no alcohol," along with its 2023 statement that recent research suggests there is "no safe level of alcohol use."

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Japan is just a few days away from running out of Asahi Super Dry as the producer of the nation's most popular beer wrestles with a devastating cyber attack that has shut down its domestic breweries. From a report: The vast majority of Asahi Group's 30 factories in Japan have not operated since Monday after the attack disabled its ordering and delivery system, the company said. Retailers are already expecting empty shelves as the outage stretches into its fourth day with no clear timeline for factories recommencing operations. Super Dry could also run out at izakaya pubs, which rely on draught and bottles. Lawson, one of Japan's big convenience stores, said in a statement that it stocks many Asahi Group products and "it is possible that some of these products may become increasingly out of stock from tomorrow onwards." "This is having an impact on everyone," said an executive at another of Japan's major retailers. "I think we will run out of products soon. When it comes to Super Dry, I think we'll run out in two or three days at supermarkets and Asahi's food products within a week or so."

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Wild chimpanzees have been found to consume the equivalent of a bottle of lager's alcohol a day from eating ripened fruit, scientists say. BBC: They say this is evidence humans may have got our taste for alcohol from common primate ancestors who relied on fermented fruit -- a source of sugar and alcohol -- for food. "Human attraction to alcohol probably arose from this dietary heritage of our common ancestor with chimpanzees," said study researcher Aleksey Maro of the University of California, Berkeley. Chimps, like many other animals, have been spotted feeding on ripe fruit lying on the forest floor, but this is the first study to make clear how much alcohol they might be consuming. The research team measured the amount of ethanol, or pure alcohol, in fruits such as figs and plums eaten in large quantities by wild chimps in Cote d'Ivoire and Uganda. Based on the amount of fruit they normally eat, the chimps were ingesting around 14 grams of ethanol -- equivalent to nearly two UK units, or roughly one 330ml bottle of lager. The fruits most commonly eaten were those highest in alcohol content.

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ScienceDaily reports: Forever chemicals known as PFAS have turned up in an unexpected place: beer. Researchers tested 23 different beers from across the U.S. and found that 95% contained PFAS, with the highest concentrations showing up in regions with known water contamination. The findings reveal how pollution in municipal water supplies can infiltrate popular products, raising concerns for both consumers and brewers... [PFAS] have been found in surface water, groundwater and municipal water supplies across the U.S. and the world. Although breweries typically have water filtration and treatment systems, they are not designed to remove PFAS... [T]he researchers call for greater awareness among brewers, consumers and regulators to limit overall PFAS exposure. These results also highlight the possible need for water treatment upgrades at brewing facilities as PFAS regulations in drinking water change or updates to municipal water system treatment are implemented. "I hope these findings inspire water treatment strategies and policies that help reduce the likelihood of PFAS in future pours," research lead Jennifer Hoponick Redmon said in a May announcement about their research.

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alternative_right shares a report from Phys.org: Some people are simply mosquito magnets while others emerge relatively unscathed. But why is this so? One explanation, according to scientists from the Netherlands, is beer. To find out why the blood-sucking critters prefer some people over others, a research team led by Felix Hol of Radboud University Nijmegen took thousands of female Anopheles mosquitoes to Lowlands, an annual music festival held in the Netherlands. Researchers set up a pop-up lab in connected shipping containers in 2023, and around 500 volunteers took part. First, they filled out a questionnaire about their hygiene, diet and behavior at the festival. Then, to see how attractive they are to mosquitoes, they placed their arm into a custom-designed cage filled with the pesky insects. The cage had tiny holes so the mosquitoes could smell the person's arm but couldn't bite them. A video camera recorded how many insects landed on a volunteer's arm compared to a sugar feeder on the other side of the cage. By comparing the video footage and questionnaire answers, researchers saw some clear results emerge. Participants who drank beer were 1.35 times more attractive to mosquitoes than those who didn't. The tiny vampires were also more likely to target people who had slept with someone the previous night. The study also revealed that recent showering and sunscreen make people less attractive to the buzzing menace. "We found that mosquitoes are drawn to those who avoid sunscreen, drink beer, and share their bed," the researchers wrote in a paper uploaded to the bioRxiv preprint server. "They simply have a taste for the hedonists among us."

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Swiss researchers have determined that fermentation degree controls beer foam stability after seven years of study published in Physics of Fluids. Triple-fermented Belgian beers maintained the longest-lasting foam while single-fermented lagers produced the shortest duration. The team tested six commercial beers including Westmalle Tripel, Tripel Karmeliet, and Swiss lagers Feldschlosschen and Chopfab. Surface viscosity dominated foam stability in single-fermented beers. Marangoni stresses from surface tension differences stabilized double- and triple-fermented beer foams. Lipid transfer protein 1 underwent progressive denaturation through successive fermentations. Single fermentation produced small round protein particles. Double fermentation created net-like protein structures. Triple fermentation broke proteins into hydrophobic and hydrophilic fragments that function as surfactants. ETH Zurich's Jan Vermant said breweries can now improve foam using these specific mechanisms rather than adjusting multiple factors simultaneously.

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Global alcohol consumption has entered what appears to be a permanent decline, with total volume peaking at 25.4 billion liters in 2016 and falling approximately 13% since then, according to data from market research firm IWSR. Per-capita consumption has dropped dramatically from 5 liters of pure alcohol per adult annually in 2013 to 3.9 liters in 2023. Wine production, which reached its maximum of 37.5 million metric tons in 1979, has already decreased by 27%. Beer production peaked more recently in 2016 at 190 million tons and has since declined 2.6%. Industry experts attribute this shift to changing generational habits, with younger consumers preferring event-driven drinking rather than habitual consumption. The proliferation of non-alcoholic alternatives, increased marijuana availability, and health consciousness accelerated by the COVID-19 pandemic have further driven moderation trends.

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An anonymous reader quotes a report from Ars Technica: Researchers at Harvard University led the study, and it included nearly 58,000 adults in Japan who were followed for up to a year using a database of medical records from routine checkups. Researchers found that when people switched from being nondrinkers to drinkers during the study, they saw a drop in their "bad" cholesterol -- aka low-density lipoprotein cholesterol or LDL. Meanwhile, their "good" cholesterol -- aka high-density lipoprotein cholesterol or HDL -- went up when they began imbibing. HDL levels went up so much, that it actually beat out improvements typically seen with medications, the researchers noted. On the other hand, drinkers who stopped drinking during the study saw the opposite effect: Upon giving up booze, their bad cholesterol went up and their good cholesterol went down. The cholesterol changes scaled with the changes in drinking. That is, for people who started drinking, the more they started drinking, the lower their LDL fell and higher their HDL rose. In the newly abstaining group, those who drank the most before quitting saw the biggest changes in their lipid levels. Specifically, people who went from drinking zero drinks to 1.5 drinks per day or less saw their bad LDL cholesterol fall 0.85 mg/dL and their good HDL cholesterol go up 0.58 mg/dL compared to nondrinkers who never started drinking. For those that went from zero to 1.5 to three drinks per day, their bad LDL dropped 4.4 mg/dL and their good HDL rose 2.49 mg/dL. For people who started drinking three or more drinks per day, their LDL fell 7.44 mg/dL and HDL rose 6.12 mg/dL. For people who quit after drinking 1.5 drinks per day or less, their LDL rose 1.10 mg/dL and their HDL fell by 1.25 mg/dL. Quitting after drinking 1.5 to three drinks per day, led to a rise in LDL of 3.71 mg/dL and a drop in HDL of 3.35. Giving up three or more drinks per day led to an LDL increase of 6.53 mg/dL and a drop in HDL of 5.65. The study has been published in JAMA Network Open.

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Friday America's surgeon general warned that alcohol is "a well-established, preventable cause of cancer responsible for about 100,000 cases of cancer and 20,000 cancer deaths annually in the United States," and recommended an update to the warning labels on alcohol. So what happens to beer and spirits companies? They've actually been preparing for something like this for years, reports CNN: Major brewers, including Molson Coors and Anheuser-Busch InBev, and spirit giants such as Diageo and Pernod Ricard, have all grown their portfolios with new non-alcoholic drinks to attract an increasing number of consumers, particularly younger ones, who are ditching drinking because of health concerns. A Gallup poll from August found that almost half of Americans say that having one or two drinks a day is bad for a person's health — the highest percentage recorded in the survey's 23 years, and younger adults were most likely to say drinking is bad for health. The poll also showed that just 58% of adults said they drink alcohol, down from 67% in 2022, although Gallup notes it's relatively close to the historical average of 63% going back to 1939. But that doesn't predict a doomsday scenario for Big Alcohol. It actually could be good for their bottom lines: A December report from IWSR, a leading drinks analysis firm, said that the non-alcoholic drinks global market is "experiencing a transformative period of growth, driven by evolving consumer behaviors and the momentum of no-alcohol." The trend, to be led by the United States, is expected to grow by $4 billion by 2028 in the firm's forecast. Non-alcoholic drinks are even "skewing younger than the core buyer demographic across markets, and demonstrate higher frequency and intensity of consumption," signaling that there's a sustained thirst for booze-less beverages. Anheuser-Busch said in its 2023 annual report that its non-alcoholic beers "continued to outperform, delivering high-teens revenue growth." And the staff economist for the Brewers Association told CNN that non-alcoholic beer sales have jumped more than 100% between 2021 and 2024.

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"Last year, a major meta-analysis that re-examined 107 studies over 40 years came to the conclusion that no amount of alcohol improves health," the New York Times reported this June, citing a study co-authored by Tim Stockwell, an epidemiologist at the Canadian Institute for Substance Use Research. Dr. Stockwell (and other scientists he's collaborated with) "are overhauling decades-worth of scientific evidence — and newspaper headlines — that backed the health benefits of alcohol," writes the Telegraph, "or what is known in the scientific community as the J-curve. The J-curve is the theory that, like a capital J, the negative health consequences of drinking dip slightly into positive territory with moderate drinking — as it benefits such things as the heart — before rising sharply back into negative territory the more someone drinks." But Stockwell's study prompted at least one scientist to accuse Stockwell of "cherry picking" evidence to suit an agenda — while a think-tank executive suggests he's a front for a worldwide temperance lobby: Dr Stockwell denies this. Speaking to The Telegraph, he in turn accused his detractors of being funded by the alcohol lobby and said his links to temperance societies were fleeting. He was the president of the Kettil Bruun Society (a think tank born out of what was the international temperance congresses) [from 2005 to 2007] and he has been reimbursed for addressing temperance movements and admits attending their meetings, but, he says, not as a member... Former British government scientist Richard Harding, who gave evidence on safe drinking to the House of Commons select committee on science and technology in 2011, told The Telegraph that Dr Stockwell had wrongly taken a correlation to be causal. "Dr Stockwell's research is essentially epidemiology, which is the study of populations," Dr Harding said. "You record people's lifestyle and then see what diseases they get and try to correlate the disease with some aspect of their lifestyle. But it is just a correlation, it's just an association. Epidemiology can never establish causality on its own. And in this particular case, Dr Stockwell selected six studies out of 107 to focus on. You could say he cherry picked them. Really, the important thing is not the epidemiology, it's the effect that alcohol actually has on the body. We know the reasons why the curve is J-shaped; it's because of the protective effect moderate consumption has on heart disease and a number of other diseases." Dr Stockwell rejects Dr Harding's criticism of his study, telling The Telegraph that Dr Harding "doesn't appear to have read it" and accusing him of being in the pocket of the alcohol industry. "We identified six high-quality studies out of 107 and they didn't find any J-shaped curve," Dr Stockwell said. "In fact, since our recent paper, we've now got genetic studies which are showing there's no benefits of low-level alcohol use. I personally think there might still be small benefits, but the point of our work is that, if there are benefits, they've been exaggerating them." The article notes that Stockwell's research "has been published in The Lancet, among other esteemed organs," and that "scientists he has collaborated with on research highlighting the dangers of alcohol are in positions of power at major institutions, such as the World Health Organisation." And honestly, the opposing viewpoint seems to be thinly-sourced. Besides Harding (the former British government scientist), the article cites: The head of lifestyle economics at the Institute of Economic Affairs (which Wikipedia describes as "a right-wing, free market think tank") An alcohol policy specialist at Brock University in Ontario (who argues rather unconvincingly that "you can't measure when someone didn't hurt themselves because a friend invited them for a drink.") On the basis of that, the article writes "respected peers say it is far from settled science and have cast doubt on his research". (And that "fellow academics and experts" told The Telegraph "they read the report in disbelief.") Did the Telegraph speak to others who just aren't mentioned in the story? Or are they extrapolating, in that famous British tabloid journalism sort of way?

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The New York Times magazine remembers that once upon a time, in the early 1990s, "some prominent researchers were promoting, and the media helped popularize, the idea that moderate drinking...was linked to greater longevity. "The cause of that association was not clear, but red wine, researchers theorized, might have anti-inflammatory properties that extended life and protected cardiovascular health..." More recently, though, research has piled up debunking the idea that moderate drinking is good for you. Last year, a major meta-analysis that re-examined 107 studies over 40 years came to the conclusion that no amount of alcohol improves health; and in 2022, a well-designed study found that consuming even a small amount brought some risk to heart health. That same year, Nature published research stating that consuming as little as one or two drinks a day (even less for women) was associated with shrinkage in the brain — a phenomenon normally associated with aging... [M]ore people are now reporting that they consume cannabis than alcohol on a daily basis. Some governments are responding to the new research by overhauling their messaging. Last year, Ireland became the first country to pass legislation requiring a cancer warning on all alcohol products sold there, similar to those found on cigarettes: "There is a direct link between alcohol and fatal cancers," the language will read. And in Canada, the government has revised its alcohol guidelines, announcing: "We now know that even a small amount of alcohol can be damaging to health." The guidelines characterize one to two drinks a week as carrying "low risk" and three to six drinks as carrying "moderate risk." (Previously the guidelines suggested that women limit themselves to no more than two standard drinks most days, and that men place that limit at three.)

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An anonymous reader shares a report: British comedian Michael McIntyre has a standard bit in his standup routines concerning the many (many!) slang terms posh British people use to describe being drunk. These include "wellied," "trousered," and "ratarsed," to name a few. McIntyre's bit rests on his assertion that pretty much any English word can be modified into a so-called "drunkonym," bolstered by a few handy examples: "I was utterly gazeboed," or "I am going to get totally and utterly carparked." It's a clever riff that sparked the interest of two German linguists. Christina Sanchez-Stockhammer of Chemnitz University of Technology and Peter Uhrig of FAU Erlangen-Nuremberg decided to draw on their expertise to test McIntyre's claim that any word in the English language could be modified to mean "being in a state of high inebriation." Given their prevalence, "It is highly surprising that drunkonyms are still under-researched from a linguistic perspective," the authors wrote in their new paper published in the Yearbook of the German Cognitive Linguistics Association. Bonus: the authors included an extensive appendix of 546 English synonyms for "drunk," drawn from various sources, which makes for entertaining reading. There is a long tradition of coming up with colorful expressions for drunkenness in the English language, with the Oxford English Dictionary listing a usage as early as 1382: "merry," meaning "boisterous or cheerful due to alcohol; slight drunk, tipsy." Another OED entry from 1630 lists "blinde" (as in blind drunk) as a drunkonym. Even Benjamin Franklin got into the act with his 1737 Drinker's Dictionary, listing 288 words and phrases for denoting drunkenness. By 1975, there were more than 353 synonyms for "drunk" listed in that year's edition of the Dictionary of American Slang. By 1981, linguist Harry Levine noted 900 terms used as drunkonyms.

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Climate breakdown is already changing the taste and quality of beer, scientists have warned. From a report: The quantity and quality of hops, a key ingredient in most beers, is being affected by global heating, according to a study. As a result, beer may become more expensive and manufacturers will have to adapt their brewing methods. Researchers forecast that hop yields in European growing regions will fall by 4-18% by 2050 if farmers do not adapt to hotter and drier weather, while the content of alpha acids in the hops, which gives beers their distinctive taste and smell, will fall by 20-31%. "Beer drinkers will definitely see the climate change, either in the price tag or the quality," said Miroslav Trnka, a scientist at the Global Change Research Institute of the Czech Academy of Sciences and co-author of the study, published in the journal Nature Communications. "That seems to be inevitable from our data." Beer, the third-most popular drink in the world after water and tea, is made by fermenting malted grains like barley with yeast. It is usually flavoured with aromatic hops grown mostly in the middle latitudes that are sensitive to changes in light, heat and water. Climate-induced decline in the quality and quantity of European hops calls for immediate adaptation measures (Nature).

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There's an ongoing study (started in 2004) that examines the effects of alcohol (and other common substances) on mood, performance, and behavior. Started by Dr. Andrea King, a professor of behavioral neuroscience at the University of Chicago, its latest result is a study called "Holding your liquor: Comparison of alcohol-induced psychomotor impairment in drinkers with and without alcohol use disorder." They found that drinkers with alcohol use disorder (or AUD, traditionally known as alcoholism) displayed less impairment on fine motor and cognitive tasks than light or heavy social drinkers after consuming a standard intoxicating dose — equivalent to four to five drinks that produce breathalyzer readings of 0.08-0.09%, i.e., the threshold for drunk driving." Yet when those drinkers with AUD consumed a higher amount akin to their usual drinking habits — equivalent to seven to eight drinks and breathalyzer readings of 0.13% — they showed significant impairment on those same tasks, more than double their impairment at the standard intoxicating dose that did not return to baseline performance three hours after drinking. "There's a lot of thinking that when experienced drinkers (those with AUD) consume alcohol, they are tolerant to its impairing effects," said Andrea King, PhD, Professor of Psychiatry and Behavioral Neuroscience at UChicago and senior author of the study. "We supported that a bit, but with a lot of nuances. When they drank alcohol in our study at a dose similar to their usual drinking pattern, we saw significant impairments on both the fine motor and cognitive tests that was even more impairment than a light drinker gets at the intoxicating dose..." While they did show less overall alcohol impairment on the motor and cognitive tests, at the 30-minute interval they had similar slowing on the fine motor test as the light drinkers. They also recovered quicker to their baseline levels, supporting the notion that they had more tolerance and can "hold their liquor" better than people who don't drink as much. However, people with AUD do not often stop drinking at four or five drinks and engage in high intensity drinking. Thus, a subset of the drinkers with AUD in the study participated in a separate session where they drank a beverage more consistent with their regular drinking habits, equivalent to about seven or eight drinks. At this higher dose of alcohol, they showed more than double the amount of mental and motor impairment than after they had the standard intoxicating dose. They also never got back to their baseline level of performance, even after three hours. Their level of impairment even exceeded that of the light drinkers who consumed the standard dose, suggesting that the physical effects of the alcohol add up the more someone drinks, experienced or not. "I was surprised at how much impairment that group had to that larger dose, because while it's 50% more than the first dose, we're seeing more than double the impairment," King said. More than 140,000 people die from excessive alcohol use in the U.S. each year, according to figures from the Centers for Disease Control and Prevention — and 30% of traffic fatalities still involve alcohol intoxication. "I'm hoping we can educate people who are experienced high-intensity drinkers who think that they're holding their liquor or that they're tolerant and won't experience accidents or injury from drinking," said Dr. King. "Their experience with alcohol only goes so far, and excessive drinkers account for most of the burden of alcohol-related accidents and injury in society. This is preventable with education and treatment." Thanks to long-time Slashdot reader WankerWeasel for sharing the article.

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"People do not like eating insects. Livestock are less picky," writes the Economist. Of course, the insects need to eat, too. To date, they have mostly been reared on leftover chicken feed. But the supply of that is limited, and if insect-reared meat is to take off, new sources will be needed. In a paper in Applied Entomology, Niels Eriksen, a biochemist at Aalborg University, suggests feeding them on the waste products of the beer industry. The world knocks back around 185bn litres of beer every year. Each litre produces between three and ten litres of wastewater full of discarded barley and yeast . The mix is rich in protein but deficient in carbohydrates, especially compared with chicken feed. The Economist reports that the researchers found brewery waste was "happily consumed" by insects they tested, which "grew equally well on either food source." This suggests the possibility that other plentiful and protein-rich food wastes could also become "reasonable targets for nutrient recycling by insects," including waste from other fermentation industries (like bioethanol), slaughterhouses, and sugar-beet waste. Thanks to Slashdot reader echo123 for sharing the article.

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"Drinking moderate amounts of alcohol every day does not — as once thought — protect against death from heart disease," writes the Washington Post, "nor does it contribute to a longer life, according to a sweeping new analysis of alcohol research." The review, which examined existing research on the health and drinking habits of nearly 5 million people, is one of the largest studies to debunk the widely held belief that moderate drinking of wine or other alcoholic beverages is good for you. Last year, researchers in Britain examined genetic and medical data of nearly 400,000 people and concluded that even low alcohol intake was associated with increased risk of disease. The new study, which appears Friday in Jama Network Open, also found that drinking relatively low levels of alcohol — 25 grams a day for women (less than 1 ounce) and 45 grams (about 1.5 ounces) or more per day for men — actually increased the risk of death. A standard wine pour is about 5 ounces. The standard serving size for beer is 12 ounces, and for distilled spirits, 1.5 ounces. "This study punctures the hope of many that moderate alcohol use is healthy," said Robert DuPont, a psychiatrist and substance abuse expert who served as the first director of the National Institute on Drug Abuse.... Much of the research into the health effects of alcohol has been funded by the alcohol industry. One recent report found that 13,500 studies have been directly or indirectly paid for by the industry.... The new review, called a "meta-analysis," looked at 107 observational studies that involved more than 4.8 million people. The study stressed that previous estimates of the benefits of moderate alcohol consumption on the risk of death by "all causes" — meaning anything, including heart disease, cancer, infections and automobile accidents — were "significantly" biased by flaws in study design. Earlier research did not adjust for numerous factors that could influence the outcome, for example, age, sex, economic status and lifestyle behaviors such as exercise, smoking and diet, they said. Using statistical software, the researchers essentially removed the bias, adjusting for various factors that could skew the research. After doing so, they found no significant declines in the risk of death by any causes among the moderate drinkers.

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A combination of psychedelics and therapy appears to help people with alcoholism cut down on the number of days per month they drink heavily, according to a new study. The Verge reports: Researchers used psilocybin, the psychedelic compound found in magic mushrooms, to treat patients over eight months and saw a dramatic improvement in participants' drinking habits. Using psychedelics as treatments for alcoholism was a popular idea in the 1960s and 1970s, and studies on LSD found that it reduced alcohol misuse. But the approach went quiet in the decades after, according to an editorial published in the journal JAMA Psychiatry alongside the new study. The new research marks a "rekindling of interest," the authors of the editorial wrote. The study included 93 people with alcohol dependence. In the 12 weeks leading up to the study, the participants drank alcohol an average of around 60 days. Of those 60 drinking days, about half were heavy drinking days -- defined as five or more drinks a day for a man and four or more drinks in a day for a woman. People in the trial were randomly assigned to either take a capsule of psilocybin or an antihistamine twice over the course of the 36-week-long study. They had four sessions with therapists before the first time they took the drug, four sessions between the two drug doses, and four sessions after the second drug dose. Everyone in the study started drinking less after the first four weeks of therapy -- the percentage of heavy drinking days dropped from around half of all drinking days to around a quarter. But that number kept falling for the people who took psilocybin. After the end of the full study, they drank heavily on around 10 percent of the days when they drank. People who took the antihistamine were still drinking heavily on around a quarter of drinking days. The effects lasted for months after the second dose of the psilocybin, study author Michael Bogenschutz, a psychiatrist and director of the NYU Langone Center for Psychedelic Medicine, stressed during a press briefing. "This suggests that psilocybin is treating the underlying disorder of alcohol addiction rather than merely treating symptoms," he said.

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