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科学誌 Cell Press Blueで発表された、病理学者かつバイオメディカル研究者のダルディ・ラミング氏が率いたレビューによれば、「より多くのたんぱく質は常に良いとは限らない」という考えが挑戦されています(ABC News 报道)。
このレビューでは、人間、マウス、昆虫、酵母など350以上の研究で、たんぱく質摂取量の減少や特定のアミノ酸摂取量の減少が健康的な老化と代謝に影響を与える可能性があることが示されました。特に、たんぱく質を減らすことで FG21ホルモンの分泌が増加し、脂肪蓄積を抑制し、エネルギー消費を促進すると指摘されました(ラミング氏)。これは、低たんぱ搾食事と体重減少、血糖値管理、代謝改善との関連性を説明する助けとなります。
しかし、たんぱく質制限はたんぱく質欠乏症とは異なり、必須栄養素の体内不足を意図的に引き起こすものではありません。研究は、すでに十分な量を摂取している人々に対して、無駄な過剰摂取を避けることで一部の人々に利益がある可能性があることを示唆しています。
高たんぱく質食品を手に取る前に、「自分の体にはどの程度のたんぱく質が必要なのか」が重要であると指摘されています。
"A major scientific review is challenging the idea that more protein is always better," reports ABC News:
The review, led by pathologist and biomedical researcher Dudley Lamming and published in the journal Cell Press Blue, examined more than 350 studies involving humans, mice, insects, yeast, and other organisms. The review found that eating less protein, or less of certain amino acids that make up protein, may turn on body processes linked to healthier aging, as well as metabolism, the process by which the body turns food and drinks into energy...
For adults who already get enough, eating more protein may offer little benefit, while some research suggests that eating less protein could support healthier aging... Lamming reviewed the effect of reducing protein in many body processes. One of the processes involves a hormone called FGF21. "There's an increase in a hormone called FGF21 that promotes energy expenditure [when protein intake is reduced]," Lamming said. "It essentially increases thermogenesis in your adipose tissue, so you don't just store fat, but actually burn it as fuel." This may help explain why some studies connect lower-protein diets with less body fat, better blood sugar control and a healthier metabolism. Eating less protein may also affect signals that tell cells when to grow, repair damage or recycle old cell parts. These jobs may play a role in aging.
However, protein restriction is not the same as protein deficiency. The goal is not to deprive the body of an essential nutrient. Instead, the research raises the possibility that avoiding unnecessary excess could benefit some people who already consume enough... Before reaching for another high-protein product, a better question may be: How much protein does my body actually need?
Read more of this story at Slashdot.